ARIAD PHARMACEUTICALS INC

CUSIP: 04033A100 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 1,834,011 Value ($000) $22,815 Avg Close — Range —
Q3 2016
Shares 1,384,174 Value ($000) $18,949 Avg Close — Range —
Q3 2015
Shares 30,458 Value ($000) $178 Avg Close — Range —
Q2 2015
Shares 704,334 Value ($000) $5,825 Avg Close — Range —
Q4 2014
Shares 52,658 Value ($000) $362 Avg Close — Range —