CEMPRA INC

CUSIP: 15130J109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 53,585 Value ($000) $1,841 Avg Close — Range —
Q1 2015
Shares 139,780 Value ($000) $4,796 Avg Close — Range —
Q4 2014
Shares 98,377 Value ($000) $2,313 Avg Close — Range —
Q4 2013
Shares 47,189 Value ($000) $585 Avg Close — Range —