HORIZON PHARMA INC

CUSIP: 44047T109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2014
Shares 78,510 Value ($000) $1,187 Avg Close — Range —
Q4 2013
Shares 170,197 Value ($000) $1,297 Avg Close — Range —
Q3 2013
Shares 10,700 Value ($000) $36 Avg Close — Range —