HYPERION THERAPEUTICS INC

CUSIP: 44915N101 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 28,907 Value ($000) $1,327 Avg Close — Range —
Q4 2014
Shares 78,956 Value ($000) $1,895 Avg Close — Range —
Q3 2014
Shares 25,482 Value ($000) $643 Avg Close — Range —