MERRIMACK PHARMACEUTICALS IN

CUSIP: 590328100 Class: CMN

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 46,387 Value ($000) $574 Avg Close — Range —
Q1 2015
Shares 380,155 Value ($000) $4,516 Avg Close — Range —
Q4 2014
Shares 399,412 Value ($000) $4,513 Avg Close — Range —
Q3 2014
Shares 143,900 Value ($000) $1,263 Avg Close — Range —
Q2 2014
Shares 69,320 Value ($000) $505 Avg Close — Range —
Q4 2013
Shares 18,921 Value ($000) $101 Avg Close — Range —