PROTALIX BIOTHERAPEUTICS INC

CUSIP: 74365A101 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 40,205 Value ($000) $74 Avg Close — Range —
Q3 2014
Shares 28,818 Value ($000) $70 Avg Close — Range —
Q2 2014
Shares 37,944 Value ($000) $138 Avg Close — Range —
Q4 2013
Shares 53,572 Value ($000) $208 Avg Close — Range —
Q3 2013
Shares 18,703 Value ($000) $85 Avg Close — Range —
Q2 2013
Shares 35,959 Value ($000) $177 Avg Close — Range —