QLT INC

CUSIP: 746927102 Class: COMMON STOCK

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 14,307 Value ($000) $29 Avg Close — Range —
Q2 2016
Shares 26,907 Value ($000) $38 Avg Close — Range —
Q1 2016
Shares 40,207 Value ($000) $80 Avg Close — Range —
Q4 2015
Shares 43,207 Value ($000) $115 Avg Close — Range —
Q3 2015
Shares 85,071 Value ($000) $226 Avg Close — Range —
Q2 2015
Shares 462,874 Value ($000) $1,912 Avg Close — Range —
Q1 2015
Shares 200,422 Value ($000) $784 Avg Close — Range —
Q4 2014
Shares 241,539 Value ($000) $969 Avg Close — Range —
Q3 2013
Shares 45,420 Value ($000) $210 Avg Close — Range —
Q2 2013
Shares 127,881 Value ($000) $562 Avg Close — Range —