SYNTA PHARMACEUTICALS CORP

CUSIP: 87162T206 Class: CMN

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 16,262 Value ($000) $4 Avg Close — Range —
Q4 2015
Shares 363,800 Value ($000) $128 Avg Close — Range —
Q4 2013
Shares 14,761 Value ($000) $77 Avg Close — Range —